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Present status and progress of neoadjuvant chemoradiotherapy for esophageal cancer

Jing Liu, Jinbo Yue, Ligang Xing, Jinming Yu

Frontiers of Medicine 2013, Volume 7, Issue 2,   Pages 172-179 doi: 10.1007/s11684-013-0268-0

Abstract: chemoradiotherapy (nCRT) followed by surgery is gaining popularity as a treatment strategy for locally advanced esophagealcancer.longer than non-responders, indicating that pCR is a significant prognostic factor for patients with esophagealcancer.

Keywords： esophageal cancer     neoadjuvant     chemoradiotherapy    

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Potential functions of esophageal cancer-related gene-4 in the cardiovascular system

Rui Zhou, Yuanshu Liu, Wenjun Huang, Xitong Dang

Frontiers of Medicine 2019, Volume 13, Issue 6,   Pages 639-645 doi: 10.1007/s11684-019-0701-0

Abstract: Esophageal cancer-related gene-4 ( ) is cloned from the normal epithelium of the esophagus.

Keywords： tumor suppressor gene     esophageal cancer-related gene-4     cardiovascular disease     hypoxia    

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The value of epigenetic markers in esophageal cancer

Xiao-Mei ZHANG, Ming-Zhou GUO,

Frontiers of Medicine 2010, Volume 4, Issue 4,   Pages 378-384 doi: 10.1007/s11684-010-0230-3

Abstract: Developing esophageal cancer is a multi-step process that begins with the accumulation of genetic andIn esophageal cancer, aberrant methylation of promoter regions occurs not only in advanced cancer, butThis review is mainly focused on epigenetic changes in esophageal cancer and the value of early detection

Keywords： epigenetics     DNA methylation     esophageal cancer     dysplasia    

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Molecular alterations and clinical relevance in esophageal squamous cell carcinoma

Li Shang, Mingrong Wang

Frontiers of Medicine 2013, Volume 7, Issue 4,   Pages 401-410 doi: 10.1007/s11684-013-0286-y

Abstract:

Esophageal squamous cell carcinoma (ESCC) is one of the most common types of gastrointestinal cancers, and the fourth leading cause of cancer-related deaths in China.Molecular classification will be useful for subtyping esophageal tumors or precancerous lesions to improve

Keywords： esophageal squamous cell carcinoma (ESCC)     early detection     molecular classification     molecular markers    

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Repurposed benzydamine targeting CDK2 suppresses the growth of esophageal squamous cell carcinoma

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 290-303 doi: 10.1007/s11684-022-0956-8

Abstract: Esophageal squamous cell carcinoma (ESCC) is one of the leading causes of cancer death worldwide.

Keywords： benzydamine     cyclin-dependent kinase 2     patient-derived xenograft     esophageal squamous cell carcinoma    

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U-shaped association between telomere length and esophageal squamous cell carcinoma risk: a case-control

Jiangbo Du,Wenjie Xue,Yong Ji,Xun Zhu,Yayun Gu,Meng Zhu,Cheng Wang,Yong Gao,Juncheng Dai,Hongxia Ma,Yue Jiang,Jiaping Chen,Zhibin Hu,Guangfu Jin,Hongbing Shen

Frontiers of Medicine 2015, Volume 9, Issue 4,   Pages 478-486 doi: 10.1007/s11684-015-0420-0

Abstract: differences of telomere length could affect predisposition to multiple cancers, but evidence regarding esophageal

Keywords： esophageal squamous cell carcinoma     telomere length     genetic variants     susceptibility     genome-wide association    

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GDF15 negatively regulates chemosensitivity via TGFBR2-AKT pathway-dependent metabolism in esophageal

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 119-131 doi: 10.1007/s11684-022-0949-7

Abstract: Treating patients with esophageal squamous cell carcinoma (ESCC) is challenging due to the high chemoresistance

Keywords： GDF15     esophageal squamous cell carcinoma     chemoresistance     cellular metabolism     TGFBR2     AKT    

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p53 functional activation is independent of its genotype in five esophageal squamous cell carcinoma cell

Junfang JI, Kun WU, Min WU, Qimin ZHAN,

Frontiers of Medicine 2010, Volume 4, Issue 4,   Pages 412-418 doi: 10.1007/s11684-010-0260-x

Abstract: mutations have been found in many esophageal squamous cell carcinoma (ESCC) clinical specimens and cell

Keywords： p53     esophageal squamous cell carcinoma     DNA damage    

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Analysis of the treatment outcomes of esophageal variceal bleeding patients from multiple centers in

WANG Zhiqiang

Frontiers of Medicine 2008, Volume 2, Issue 2,   Pages 171-173 doi: 10.1007/s11684-008-0031-0

Abstract: This study aimed to investigate the treatment outcomes of esophageal variceal bleeding (EVB) in China

Keywords： significant difference     predictive     medication     first-line treatment     bleeding    

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Esophageal pulse oximetry is more accurate and detects hypoxemia earlier than conventional pulse oximetry

Guo Chen, Zhaoqiong Zhu*, Jin Liu, Wei Wei

Frontiers of Medicine 2012, Volume 6, Issue 4,   Pages 406-410 doi: 10.1007/s11684-012-0217-3

Abstract: The goal of this study was to evaluate the sensitivity and accuracy of an esophageal pulse oximetry probeAfter tracheal intubation, an esophageal probe was placed in the lower segment of the esophagus for esophageal

Keywords： esophageal pulse oximetry     conventional pulse oximetry     hypoxemia    

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Surgical treatment of hepatocellular carcinoma with cirrhotic esophageal varices and hypersplenism: a

JIANG Bin, CHEN Xiaoping, HUANG Zhiyong, ZHANG Zhiwei, HE Songqing, WANG Shaofa, WU Zaide, QIU Fazu

Frontiers of Medicine 2007, Volume 1, Issue 1,   Pages 24-29 doi: 10.1007/s11684-007-0005-7

Abstract: carcinoma (HCC) patients with advanced cirrhosis, one of the most difficult problems is concomitant esophagealTo elucidate whether esophageal devascularization or splenectomy is beneficial when simultaneously performedvarices and hypersplenism received one of the three treatments: simultaneous liver resection and esophagealThe results suggest that HCC patients with esophageal varices and hypersplenism should undergo hepaticresection plus esophageal devascularization or splenectomy if radical resection of HCC can be expected
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Midline2 is overexpressed and a prognostic indicator in human breast cancer and promotes breast cancer

Frontiers of Medicine 2021, Volume 15, Issue 6,   Pages 942-942 doi: 10.1007/s11684-021-0876-z

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Clinical response with functional image during radiotherapy of esophageal squamous cell carcinoma

Yu Jinming

Strategic Study of CAE 2012, Volume 14, Issue 7,   Pages 9-19

Abstract:

18F-FLT uptake can be used to monitor the biological response of esophagealbeginning of treatment and estimate clonogenic repopulation during RT. 18F-FETNIM PET can depict hypoxia in esophageal

Keywords： esophageal carcinoma     radiotherapy     positron emission     tomography accelerated repopulation     hypoxia    

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Progress and challenges in RET-targeted cancer therapy

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 207-219 doi: 10.1007/s11684-023-0985-y

Abstract: Oncogenic RET fusions or mutations are found most often in non-small cell lung cancer (NSCLC) and inthyroid cancer, but also increasingly in various types of cancers at low rates.

Keywords： pralsetinib     selpercatinib     RET-alteration     lung cancer     thyroid cancer     tumor-agnostic therapy     drug    

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Epithelial-to-mesenchymal transition in cancer: complexity and opportunities

Yun Zhang, Robert A. Weinberg

Frontiers of Medicine 2018, Volume 12, Issue 4,   Pages 361-373 doi: 10.1007/s11684-018-0656-6

Abstract: termed the epithelial-to-mesenchymal transition (EMT) plays an important role in both development and cancerinvasiveness, drug-resistance and the ability to form metastases at distant organs, and thereby contribute to cancer

Keywords： epithelial-to-mesenchymal transition     cancer     metastasis     cancer stem cell    

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Title Author Date Type Operation

Present status and progress of neoadjuvant chemoradiotherapy for esophageal cancer

Jing Liu, Jinbo Yue, Ligang Xing, Jinming Yu

Journal Article

Potential functions of esophageal cancer-related gene-4 in the cardiovascular system

Rui Zhou, Yuanshu Liu, Wenjun Huang, Xitong Dang

Journal Article

The value of epigenetic markers in esophageal cancer

Xiao-Mei ZHANG, Ming-Zhou GUO,

Journal Article

Molecular alterations and clinical relevance in esophageal squamous cell carcinoma

Li Shang, Mingrong Wang

Journal Article

Repurposed benzydamine targeting CDK2 suppresses the growth of esophageal squamous cell carcinoma

Journal Article

U-shaped association between telomere length and esophageal squamous cell carcinoma risk: a case-control

Jiangbo Du,Wenjie Xue,Yong Ji,Xun Zhu,Yayun Gu,Meng Zhu,Cheng Wang,Yong Gao,Juncheng Dai,Hongxia Ma,Yue Jiang,Jiaping Chen,Zhibin Hu,Guangfu Jin,Hongbing Shen

Journal Article

GDF15 negatively regulates chemosensitivity via TGFBR2-AKT pathway-dependent metabolism in esophageal

Journal Article

p53 functional activation is independent of its genotype in five esophageal squamous cell carcinoma cell

Junfang JI, Kun WU, Min WU, Qimin ZHAN,

Journal Article

Analysis of the treatment outcomes of esophageal variceal bleeding patients from multiple centers in

WANG Zhiqiang

Journal Article

Esophageal pulse oximetry is more accurate and detects hypoxemia earlier than conventional pulse oximetry

Guo Chen, Zhaoqiong Zhu*, Jin Liu, Wei Wei

Journal Article

Surgical treatment of hepatocellular carcinoma with cirrhotic esophageal varices and hypersplenism: a

JIANG Bin, CHEN Xiaoping, HUANG Zhiyong, ZHANG Zhiwei, HE Songqing, WANG Shaofa, WU Zaide, QIU Fazu

Journal Article

Midline2 is overexpressed and a prognostic indicator in human breast cancer and promotes breast cancer

Journal Article

Clinical response with functional image during radiotherapy of esophageal squamous cell carcinoma

Yu Jinming

Journal Article

Progress and challenges in RET-targeted cancer therapy

Journal Article

Epithelial-to-mesenchymal transition in cancer: complexity and opportunities

Yun Zhang, Robert A. Weinberg

Journal Article